Box plots of percentage of risky combinatory genotypes carried in the subjects who were identified by one of the fourteen gene clusters in the five datasets. Each box in the left-hand side shows the shared gene and the number of involved genes in a gene clusters. Red box plots represent HT patients, whereas blue box plots are for NC subjects. The horizontal dashed line represents the cut-off percentage of risky combinatory genotypes for defining HT computed for each data set. ER denotes classification error.