Table 2 The maximum absolute difference in power (over the respective causal genes) between weighting and collapsing pooling strategies for different tests and phenotypes in GAW17 data set
From: Comparison of similarity-based tests and pooling strategies for rare variants
Scenario/Test | MDMR | SKAT | KBAT | U-Test |
|---|---|---|---|---|
Q1 | 0.84 (KDR) | 0.45 (ARNT) | 0.22 (ARNT) | 0.145 (HIF3A) |
Q2 | 0.605 (VNN1) | 0.5 (VNN1) | 0.42 (VNN1) | 0.535 (VNN1) |
Dichotomous | 0.77 (FLT1) | 0.42 (PRKCA) | 0.43 (PRKCA) | 0.535 (FLT1) |