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Figure 3 | BMC Genomics

Figure 3

From: Accurate single nucleotide variant detection in viral populations by combining probabilistic clustering with a statistical test of strand bias

Figure 3

Precision recall curves for various strand bias tests. Precision versus recall, for strand bias tests performed on raw SNV calls from (a) ShoRAH applied to HCV run 1, (b) VarScan applied to HCV run 1, (c) ShoRAH applied to HCV run 2, and (d) VarScan applied to HCV run 2. In all cases, strand bias tests based on an underlying beta-binomial forward read distribution exhibited greater or equal precision for the same recall value, when compared to either a strand bias test with a binomial forward read distribution, or a Fisher’s exact test of strand bias.

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BMC Genomics

ISSN: 1471-2164

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