Figure 9
From: Discovery of structural alterations in solid tumor oligodendroglioma by single molecule analysis
Strategy for assembling the ~500 kb inversion in the Williams-Beuren region in HF1551. A: Construction of the modified, ‘hypothesis’ reference map for directed assembly. The map has a ~500 kb inversion in the center, flanked on either side by 500 kb of sequence that agrees with the reference map. B: After 8 iterations of map assembly, an optical consensus map is obtained that spans the hypothesized reference, and has multiple Rmaps that bridges across both left and right breakpoints.