Figure 1

Pooling-specific error. The absolute difference (error) of the A allele frequency obtained using pooled DNA samples (y-axis) compared to the expected allele frequency based on individual genotyping using the corresponding RAS calculation method (x-axis). Birdseed2: uncorrected RAS values obtained using the Birdseed2 algorithm; CEL: uncorrected RAS values obtained from CEL files; k: k-corrected RAS value; n: tan-correction using the specified value for n as parameter; PPC: PPC corrected RAS values. The horizontal lines represent the median error, the bars show the 90% quantile and the length of the whiskers corresponds to the standard deviation of the error. The plots show the error of DNA-Pool 1 (left) and DNA-Pool 2 (right), estimated using the MAF >1% SNP set.