Figure 11
Summary of Confero Bioconductor estrogen dataset GSEA results and leveraging of leading edge genes results from Export Leading Edge Matrix tool. Grouping gene sets per biological processes and investigating the leading edge genes associated to significantly enriched gene sets enables to rapidly interpret biological events at the molecular level and raise new hypothesis that could further be experimentally verified. Red and green colors highlight normalized enrichment scores that are significantly enriched for up- or down-regulated genes, respectively.