Figure 6

Overrepresented motifs upstream of ribosomal protein genes in P. falciparum and C. parvum . A. Expression profiles for 68 P. falciparum (Pf) co-expressed IDC ribosomal proteins (data from Bozdech et al. 2003). B. Expression profiles for 25 C. parvum (Cp) co-expressed ribosomal proteins from clusters #6, #20 and #35. Five representative upstream regions are shown for each organism out of 68 Pf and 60 Cp respectively. Upstream regions for each of these genes were mined for overrepresented motifs (see Materials and Methods). As previously documented, the upstream regions of Pf ribosomal proteins contain overrepresented G-box motifs (Essien and Stoeckert, 2010). Cp ribosomal proteins have E2F-like and GAGA-like motifs overrepresented upstream.