Whole-genome resequencing of Hanwoo (Korean cattle) and insight into regions of homozygosity

BMC Genomics

Table 2 Summary of specific regions of homozygosity (ROHs) in Hanwoo, Black Angus, and Holstein

	Breed	No. of ROHs	ROH size (Mb)	Average ROH size (Mb)	Gene count	Trait-associatedgene count	NS/SS/I²(novel)
ROH	Hanwoo	16	114.4	7.15	753	24	1,133 (762)
	Black Angus	78	176.8	2.26	1321	46	1,946 (1,289)
	Holstein	51	354	6.94	2483	68	3,905 (2,657)
sROH ¹	Hanwoo	19	102.4	5.39	650	19	968 (675)
	Black Angus	67	147.6	2.2	1109	41	1,625 (1,087)
	Holstein	56	332	5.93	2322	64	3,693 (2,512)

¹ sROH: ROH specific to a breed identified by comparing ROHs among breeds. A single ROH can produce more than one sROH when a middle portion of the ROH is present in another breed such that the two outer regions of the ROH are specific to a breed. Alternatively, if an entire ROH is present in more than one breed it is not counted as a sROH in any breed.
²NS/SS/I non-synonymous SNP/splice-site variation/coding indel.

ISSN: 1471-2164