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Figure 2 | BMC Genomics

Figure 2

From: miRNA and miRNA target genes in copy number variations occurring in individuals with intellectual disability

Figure 2

Genomic coverage of miRNA (A) and protein coding genes (B) in different CNV subgroups. The fraction was defined as observed number of miRNA (or protein coding genes) in each CNV group divided by the total miRNAs (or total number of protein coding genes) in human genome. The miRNA or gene fraction in CNVs was compared to the miRNA or gene fraction in the reference genome which was generated by extracting random DNA fragments with similar length to the respective CNVs 1000 times from human genome. * Indicates p < 0.05 (a Wilcoxon signed-rank test). 1: De novo CNVs; 2: DECIPHER CNVs; 3: Familial CNVs; 4: Common CNVs from controls; 5: Common CNVs from cases.

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