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Figure 5 | BMC Genomics

Figure 5

From: Human growth is associated with distinct patterns of gene expression in evolutionarily conserved networks

Figure 5

Heat map of age-associated changes in the expression of genes for glucocorticoid receptor interacting proteins (n = 338) in 87 individuals (0.2 to 29.3 years of age - average 7.7+/−7.0 yrs); 35 gene expression probes were significantly associated with age (ANOVA, false discovery rate (FDR) corrected p-value, q < 0.2). Supervised hierarchical clustering using Kendell’s dissimilarity and Ward’s method identified three main clusters of gene expression probes correlating with ≤6 years of age [infancy, early childhood group (15 probes)]; >6 to ≤17 years of age [late childhood, puberty group (12 probes)] and >17 to <30 years of age [adulthood (8 probes)]. Gene expression is shown between +2.5 fold and −2.5 fold, red = increase in gene expression, green = decrease in gene expression.

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