Table 3 Replication results for the already-described loci
SNP REF | LOCUS | REPORTED ALLELE | REPORTED MAF | ALLELIC OR (95% CI) | BEST PROXY AFFY 6.0 | R2 | OR (95% CI) | EPICOLON P value |
|---|---|---|---|---|---|---|---|---|
rs6687758 | 1q41 | G | 0.2 | 1.09 (1.06-1.12) | rs6691195 | 1 | 1.10 (0.92-1.33) | 0.291 |
rs6691170 | 1q41 | T | 0.34 | 1.06 (1.03-1.09) | rs11579490 | 0.902 | 1.00 (0.86-1.17) | 0.974 |
rs10936599 | 3q26 | T | 0.24 | 0.93 (0.91-0.96) | rs7621631 | 1 | 0.99 (0.83-1.19) | 0.970 |
rs16892766 | 8q23 | C | 0.07 | 1.32 (1.21-1.44) | rs2437844 | 0.925 | 1.13 (0.87-1.46) | 0.360 |
rs6983267 | 8q24 | T | 0.48 | 0.83 (0.79-0.87) | rs6983267 | - | 0.87 (0.75-1.01) | 0.065 |
rs10795668 | 10p14 | A | 0.33 | 0.91 (0.86-0.96) | rs706771 | 0.896 | 0.89 (0.76-1.04) | 0.15 |
rs3802842 | 11q23 | C | 0.29 | 1.21 (1.15-1.27) | rs3802840 | 1 | 1.19 (1.01-1.40) | 0.037 |
rs11169552 | 12q13 | T | 0.26 | 0.92 (0.90-0.95) | rs11169544 | 1 | 0.99 (0.83-1.18) | 0.891 |
rs7136702 | 12q13 | T | 0.35 | 1.06 (1.03-1.09) | rs7136702 | - | 1.14 (0.98-1.33) | 0.0806 |
rs4444235 | 14q22 | C | 0.46 | 1.12 (1.07-1.18) | rs11623717 | 0.838 | 1.01 (0.88-1.17) | 0.859 |
rs1957636 | 14q22 | A | 0.39 | 1.08 (1.06-1.11) | rs4901475 | 0.932 | 1.16 (0.99-1.34) | 0.153 |
rs16969681 | 15q13 | T | 0.09 | 1.18 (1.11-1.25) | rs16969344 | 1 | 1.21 (0.96-1.53) | 0.103 |
rs11632715 | 15q13 | A | 0.46 | 1.12 (1.08-1.16) | rs12592288 | 0.524 | 1.04 (0.81-1.12) | 0.589 |
rs9929218 | 16q22 | A | 0.29 | 0.88 (0.83-0.92) | rs7186084 | 1 | 0.94 (0.80-1.10) | 0.439 |
rs4939827 | 18q21 | C | 0.47 | 0.85 (0.81-0.89) | rs7226855 | 1 | 0.82 (0.71-0.95) | 8.204E-03 |
rs10411210 | 19q13 | T | 0.10 | 0.79 (0.72-0.86) | rs7252505 | 0.831 | 0.90 (0.72-1.13) | 0.363 |
rs961253 | 20p12 | A | 0.36 | 1.13 (1.08-1.19) | rs5005940 | 1 | 1.11 (0.92-1.26) | 0.349 |
rs4813802 | 20p12 | G | 0.36 | 1.09 (1.06-1.12) | rs4813802 | - | 1.07 (0.91-1.25) | 0.433 |
rs4925386 | 20q13 | T | 0.32 | 0.93 (0.91-0.95) | rs4925386 | - | 0.96 (0.82-1.12) | 0.61 |