Characterization of constitutive CTCF/cohesin loci: a possible role in establishing topological domains in mammalian genomes

Table 3 Proportions of various CTCF binding sites that contained within the CTCF-mediated interaction regions from ChIA-PET

Comparison	Total sites	Sites in interaction		Odds ratio	P-value
Comparison	Total sites	Number	Proportion	Odds ratio	P-value
(A) K562
cCTCF	23,577	14,178	0.60	7.7	~0
All CTCF excluding cCTCF	81,464	13,316	0.16	7.7	~0
cCTCF/cCohesin	12,014	8,714	0.73	2.9	~0
cCTCF excluding cCohesin	11,563	5,464	0.47	2.9	~0
(B) MCF7
cCTCF	23,641	19,398	0.82	8.5	~0
All CTCF excluding cCTCF	67,752	23,701	0.35	8.5	~0
cCTCF/cCohesin	12,001	10,796	0.90	3.2	4×10^-227
cCTCF excluding cCohesin	11,640	8,602	0.74	3.2	4×10^-227

ISSN: 1471-2164