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Figure 5 | BMC Genomics

Figure 5

From: Global expression profiling reveals genetic programs underlying the developmental divergence between mouse and human embryogenesis

Figure 5

Most of the up- and down-regulated genes are common during mouse and human organogenesis. (A) Venn diagrams between mouse and human genes whose expression significantly changed during organogenesis. (B-D) Venn diagrams of the subsets of genes in panel (A) that were up- (B), down- (C), and arch-up- (D) regulated, respectively. (E-G) Heat-map expression profiles of the common genes between human and mouse in B–D, respectively. (H-I) Heat-map expression profiles of selected genes involved in 4 signaling processes that are up- (H) or down- (I) regulated similarly during organogenesis in mouse and human.

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