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Table 1 Common and unique biological function of genes bound by RXRα coupled with RARα, PXR, LXR, FXR and PPARα

From: The role of retinoic acid in hepatic lipid homeostasis defined by genomic binding and transcriptome profiling

Pathways

RARα

PXR

LXR

FXR

PPARα

Acylglycerol metabolic process

  

1.9E-07

 

3.8E-10

Neutral lipid metabolic process

  

2.7E-07

 

9.4E-10

Glycerol ether metabolic process

  

2.7E-07

 

1E-10

Organic ether metabolic process

    

4.5E-11

Carboxylic acid catabolic process

6.1E-11

7.3E-07

2.8E-08

1.9E-09

6.1E-11

Organic acid catabolic process

6.1E-11

7.3E-07

2.8E-08

1.9E-09

6.1E-11

Coenzyme metabolic process

9.4E-13

  

2E-07

1.7E-10

Cofactor metabolic process

1.6E-17

3.0E-06

 

2.1E-07

2E-11

Fatty acid metabolic process

    

1.8E-12

Oxidation reduction

1.7E-23

1E-11

1.4E-16

6.1E-14

3.4E-28

Sterol homeostasis

  

7.2E-08

  

Cholesterol homeostasis

  

7.2E-08

  

Lipid homeostasis

   

4.8E-07

 

Lipid transport

   

2E-07

 

Hexose metabolic process

   

2.1E-07

 

Steroid metabolic process

  

2.6E-11

2E-08

 

Monosaccharide metabolic process

   

1.4E-07

 

Pyruvate metabolic process

 

1.3E-05

   

Acute-phase response

 

3.2E-05

   

Cellular carbohydrate biosynthetic process

 

5.9E-06

   

Acute inflammatory response

 

7.3E-07

   

Glucose metabolic process

 

0.00001

   

Response to wounding

 

3.5E-07

   

Electron transport chain

2.7E-10

    

ncRNA metabolic process

4.2E-15

 

1.8E-09

  

mRNA processing

6.7E-16

    

Translation

7E-16

    

RNA processing

8.8E-16

    
  1. Numbers in the table represent the p value given by DAVID.