Modelling mutational and selection pressures on dinucleotides in eukaryotic phyla –selection against CpG and UpA in cytoplasmically expressed RNA and in RNA viruses

Table 1 Comparison of the first three context-dependent mutations and mutation rates in three mammalian species

Seq.	Species	κ	Corrected model error	1^st	Rate	2^nd	Rate	3^rd	Rate
DNA	H. sapiens	3.1	0.0135	C→T,G	12.06	G→T,T	6.16	A→G,T	1.42
	P. troglodytes	4.6	0.0134	C→T,G	11.29	G→T,T	6.01	A→G,T	1.30
	M. musculus	4.6	0.0117	C→T,G	14.33	G→T,T	4.30	C→G,A	2.20
RNA	H. sapiens	1.7	0.0249	C→U,G	10.26	U,A→C	9.53	C→A,G	9.40
RNA	P. troglodytes	1.6	0.0265	C→U,G	10.17	U,A→C	11.93	C→A,G	10.00
	M. musculus	1.6	0.0183	C→U,G	10.84	U,A→C	9.48	C→A,G	10.73

ISSN: 1471-2164