Figure 4

Extension and contraction of selected protein families. Proteins were classified into families according to the Pfam database, and the number of representatives in each family was analysed with the CAFE software. All families shown were significantly expanded (upward arrow) or contracted (downward arrow) in the proteome of Wallemia ichthyophaga. The numbers of representatives of each protein family in the contemporary species as well as the estimated ancestral states are shown in the trees. Statistically significant numbers for W. ichthyophaga, W. sebi and their last common ancestor are marked with an asterisk. The chronogram of analysed species was reconstructed on the basis of whole proteomes, and calibrated according to previously published calibration points in the fungal tree of life (scale unit, millions of years). A. Protein family of fungal hydrophobins (PF01185). B. Protein family of cation transporting (P-type) ATPases (PF00690). C. Major facilitator superfamily (MFS) and sugar transporters (PF07690, PF00083). D. Protein families of amino-acid permeases and transporters (AA uptake; PF13520, PF01490). E. Protein families of ATP binding cassette (ABC) transporters (PF01061, PF00664, PF00005, PF06422).