Figure 2

Differential gene expression profile between wild-type P. aeruginosa PAO1 and a parS (A) and a parR (B) mutant. Each point represents one of the 5570 annotated genes in the PAO1 genome, with the x-axis showing gene order (from the DNA replication origin), and the y-axis showing the log₂ of transcript abundance for each gene in the parS or parR mutant relative to the wild-type (WT) strain. The arrows point to a few genes or gene clusters that are differentially expressed in both parS and parR mutants. pqsABCDE: PQS signal biosynthetic genes. phzA2: phenazine biosynthetic gene; mexEF-oprN: RND efflux pump operon; PA1970, PA3229, PA4881: hypothetical proteins; PA3326-PA3336: A 16.6 kb region including clpP2 (ATP-dependent Clp protease), fabH2 (3-oxoacyl-[acyl-carrier-protein] synthase III) and many hypothetical genes.