Figure 4

Model showing the major differences in the processes regulated by ArcA after H ₂ O ₂ exposure under aerobic conditions, aerobiosis and anaerobiosis in S. Typhimurium 14028s. Each symbol represents groups of genes that are functionally related and are colored based on the degree of regulation by ArcA under each condition. Data from anaerobic conditions was obtained from [8]. Blue shows that the genes are positively regulated by ArcA, yellow shows that the genes are not affected by ArcA, and red shows that the genes are negatively regulated by ArcA. G-3-P: glyceraldehyde 3 phosphate, PDH: pyruvate dehydrogenase complex, TCA cycle: tricarboxylic acid cycle, GSSG: oxidized glutathione, Trx-[S]₂: oxidized thioredoxin.