Table 1 Major categories of machine-learning methods for analysis of microbiome samples with sequencing data
From: Alignment-free supervised classification of metagenomes by recursive SVM
Data type | Metegnome sequencing | 16S rRNA | |||
|---|---|---|---|---|---|
Feature type | Alignment-free | Alignment-based | OTU-based or microbial taxon-based | ||
(based on sequence signature features without using any database) | (based on features obtained by mapping sequence reads to annotation databases) | ||||
Type of machine learning | Supervised classification | Unsupervised clustering | Supervised classification | Unsupervised clustering | Supervised or unsupervised |