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Figure 2 | BMC Genomics

Figure 2

From: Integrated genomic analysis of triple-negative breast cancers reveals novel microRNAs associated with clinical and molecular phenotypes and sheds light on the pathways they control

Figure 2

Prognostic miRNAs in ER-negative and triple-negative tumour sub-cohorts (log-rank p-value < 0.002 and FDR q-value < 0.2). Chromosomal positions are indicated, except from miR-548d-5p, which co-locates with a DNA transposable element (TE). Left Panel: Results from independent Cox-regression analyses run on triple-negative and ER-negative tumours Right Panel: Association between miRNA expression and DNA gains/losses. Filled blue bars represent Spearman correlation values. Shaded bars represent the -log10 q-value of the Wilcoxon test, resulting from the comparisons of tumours with DNA gains (red bars) and losses (green bars) to tumours without DNA changes.

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BMC Genomics

ISSN: 1471-2164

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