Distributions of interspecific conserved (CMC) and species differential (DMC) mCs in different functional elements. (A) Proportion of CMCs and DMCs in different genomic functional regions. (B), (C) Analysis of CMCs (B) and DMCs (C). Two-kilobase regions upstream and downstream of each gene were divided into 100-base pair (bp) intervals. Each gene was divided into 20 intervals (5% per interval). Plots show methylation density in each interval. Dome, domesticated silkworm specific; Wild, wild silkworm specific.