Representation of NRPS sequences of Xanthomonas spp. strain XaS3. A. Representation of contigs of Xanthomonas spp. strain XaS3 that contain a nucleotide sequence encoding at least one A domain and/or a nucleotide sequence encoding non-NRPS genes similar to genes found in the locus META-B of strain X. albilineans GPE PC73. B. Comparison of the locus META-A of X. albilineans strain GPE PC73 with the two contigs of Xanthomonas spp. strain XaS3 predicted to belong to a locus similar to this locus META-A. Brown arrows: staM and staM’ genes predicted to be required for β-hydroxylation of two unidentified amino acids, respectively. Purple arrow: daT gene predicted to be required for biosynthesis of Dab (2,4-diamino butyric acid). Orange arrows: genes predicted to be required for biosynthesis of Dpg (3,5-dihydroxyphenyl-glycine). Dark blue arrows: other genes conserved in all META-B loci (ABC transporter, MbtH-like protein and transcriptional regulator AraC). Green arrows and yellow arrow: genes conserved in strains X11-5A and XaS3 predicted to be required for biosynthesis of an unknown non-proteinogenic amino acid (Hp: hypothetical protein gene; TA: transaminase gene; DH: lactate dehydrogenase gene). Black arrows: NRPS genes. Length of arrows is not proportional to the length of genes. All information regarding characteristics and color-code for NRPS modules are as detailed in Figure 2. IS: insertion sequence. XALB1: albicidin biosynthesis gene cluster. Incomplete circles: incomplete nucleotide sequence located at the end or at the beginning of a contig encoding only one part of a module.