Figure 1

Protease production and process parameters. Process parameters are shown for fermentation L (the parameters for the replicate fermentations R and M are corresponding, data not shown). Temperature T [°C], oxygen partial pressure pO₂ [%], glucose concentration c_Glucose [g/L], supplied glucose feed_Glucose [g/L] and normalized protease activity [%] are displayed on left y-axis, whereas acetate concentration c_Acetate [g/L] and carbon dioxide content CO₂ [%] are scaled on the right y-axis. Process time t [h] is given on the x-axis. The sampling points I to V are indicated by orange lines.