Genome-wide analysis of human hotspot intersected genes highlights the roles of meiotic recombination in evolution and disease

Table 1 Comparison of evolutionary rates

Dataset	dN	dS	dN/dS
HK	- (***)	- (***)	- (***)
TiGER	+ (***)	+ (***)	+ (***)
SPD	+ (***)	+ (***)	+ (***)
MI	- (**)	- (***)	-
CI	- (***)	- (***)	- (**)

The dN, dS and dN/dS values of HK genes, TiGER genes, SPD genes, MI genes and CI genes are compared to HI genes. The symbol ‘-’ indicates the median value is less than HI genes and ‘+’ indicates the median value is greater than HI genes. The symbol ‘***’ indicates a p value less than 0.001 and ‘**’ indicates a p value less than 0.01.

ISSN: 1471-2164