Figure 3

Hierarchical clustering of mRNA expression profiles in liver tissue for age-matched and size-matched wild-type fish. Heatmap of hierarchical clustering using Euclidian distance measurement on mRNAs with significantly different expression (P ≤ 0.05 and fold change ≥ 2) between Wa relative to Ws groups (individual samples). The X-axis is clustered by group (condition) and the Y-axis by normalised mRNA expression values. Hierarchical clustering of individual fish grouped the fish according to age-matched wilds (Wa) and size-matched wilds (Ws). The expression bar indicates the normalised expression level for each mRNA, which are represented by various colour intensities.