Chromosome 12 (Rotarod) | Proposed function | # SNPs different between strains | SNP locations |
---|---|---|---|
Vsnl1 | Neuronal Ca2+ sensor proteins | 24 | All I |
Ddx1 | Viral responses | 2 | All I |
Trib2 | Induces apoptosis of cells in hematopoietic origin; CD8 T cells | 40 | 1 Cs, 1 U5, 38 I |
Lpin1 | Demyelination; actin cytoskeleton reorganization | 531 | 3 Cn, 8 Cs, 27 U3, 493 I |
Kcnf1 | Neurotransmitter release; neuronal excitability | 35 | 4 Cs, 7 U5, 24 U3 |
Rock2 | Actin cytoskeleton organization; regulation of angiogenesis | 330 | 1 Cn, 3 Cs, 5 U3, 321 I |
Chromosome 17 (CNS vascular permeability) | Proposed function | # SNPs different between strains | SNP locations |
Pde10a | Signal transduction; neuronal cell bodies | 1268 | Unspecified |
Qk | Myelinization; axon ensheathment; vasculogenesis | 214 | 12 U3, 202 I |
Pacrg | Myelinization | 265 | 2 U5, 263 I |
Park2 | Neuron projection; neuron death | 3198 | 2 Cs, 1 U3, 3195 I |
Plg | Apoptotic processes; vessel development | 38 | 1 Cn, 37 I |
Igf2r | Edema | 7 | All I |
Mas1 | Inflammatory responses | 2 | All I |
Mllt4 | Adherens junctions; cell junctions | 7 | All I |