Figure 2

The 8–16 translocation and impact on fermentation. (A) CGH profile for the segregant 7a (in red) which has the partial disomy, in comparison to S288C CGH profile (in black). (B) Parental and daughter genotype: Crossing 59A which has the translocation with S288c gives four types of segregants: without translocation (S288c like), with the translocation (59A like), with two chr16 left arm (partial disomy) or without chr16 left arm but this combination is not viable, due to the loss of essentials genes (e.g. NSL1, NAB3, RPL5). (C) Average fermentation profile for the normal segregants (black) and disomic segregants (red). The doted lines represent standard error. Kinetics are represented in function of time (left) or of CO₂ release (right).