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Figure 2 | BMC Genomics

Figure 2

From: DNMT1 and AIM1 Imprinting in human placenta revealed through a genome-wide screen for allele-specific DNA methylation

Figure 2

Methylation concordance in known gDMRs and CGIs with partial methylation. (A) Comparison of concordance for known gDMRs vs. other CGIs with partial methylation (30-70% methylation): known gDMRs showed much higher concordance levels than partially methylated CGIs. P1: first trimester placenta; P3: third trimester placenta. (B) There were 495 CGIs with partial methylation and high concordance shared between the first trimester and third trimester placentas. (C) Genomic mapping of CGIs with partial methylation and high concordance showed that the CGIs were distributed across promoters (blue), gene bodies (red) and intergenic regions (green). Gene body regions contained the highest number of such CGIs in both the first and third trimester placenta.

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BMC Genomics

ISSN: 1471-2164

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