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Figure 4 | BMC Genomics

Figure 4

From: Inter- and intra-specific pan-genomes of Borrelia burgdorferi sensu lato: genome stability and adaptive radiation

Figure 4

Pan- genome calculations of the conserved core, predicted new genes and pan-genome size of 21 B. burgdorferi s. s. and s. l. isolates. The pan-genome calculations displayed in the figure were performed in order to gain insight about the entire genomic diversity of the B. burgdorferi s.l. group. (A), Each colored data point represents values of the number of conserved genes calculated for different combinations of n compared genomes (n value plotted on the x-axis). The exponential decay model (black solid line), based on the median value for conserved genes when increasing numbers of genomes are compared, predicts a conserved gene core for Borrelia sp. of 1200 genes. (B) Plot showing decreasing numbers of predicted new genes with increasing number of genomes compared. The black line shows the exponential decay model based on the median value for new genes when increasing numbers of genomes were compared. (C) The extrapolated curve plateaus at a value of 1859 genes, that is reached for a total of 21 genomes, highlighting the fact that there is some genomic diversity left to be discovered in B. burgdorferi s.l. isolates.

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