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Table 3 Differentially expressed Go biological processes in response to map infection inside MAC-T cells

From: Host-Mycobacterium avium subsp. paratuberculosis interactome reveals a novel iron assimilation mechanism linked to nitric oxide stress during early infection

 

GO process

Number of genes

P-Value

Benjamini score

Upregulated

Cell cycle process

36

2.42E-12

2.43E-09

M phase

2

7.38E-12

3.71E-09

Nuclear division

15

8.97E-12

3.01E-09

Mitosis

30

8.97E-12

3.01E-09

Cell division

2

1.29E-11

3.24E-09

M phase of mitotic cell cycle

15

1.81E-11

3.65E-09

Organelle fission

30

2.15E-11

3.60E-09

Cell cycle phase

18

2.36E-11

3.40E-09

Cell cycle

8

4.14E-11

5.21E-09

Mitotic cell cycle

16

1.17E-10

1.30E-08

Microtubule-based process

12

3.14E-05

0.00315028

DNA metabolic process

15

3.99E-05

0.003643606

DNA replication

9

4.40E-05

0.003681565

Microtubule-based movement

9

7.00E-05

0.00540001

DNA replication initiation

4

1.80E-04

0.0128323

Negative regulation of molecular function

8

5.69E-04

0.03743265

Downregulated

Immune response

19

1.06E-05

0.011956577

Regulation of protein kinase activity

10

1.17E-04

0.064589297

Regulation of kinase activity

10

1.76E-04

0.064494576

Ear development

7

1.94E-04

0.053853857

Regulation of phosphorylation

12

1.96E-04

0.043562316

Regulation of transferase activity

9

2.27E-04

0.042105651

Regulation of cell proliferation

15

2.64E-04

0.042029006

Regulation of phosphorus metabolic process

12

2.89E-04

0.040342208

Regulation of phosphate metabolic process

12

2.89E-04

0.040342208

 

Negative regulation of protein kinase activity

6

3.44E-04

0.042649138