Table 1 Comparison of GO terms for genes under positive selection for the white shark, two teleosts, and six mammals

Biological regulation

Response to stimulus

Regulation of transcription from RNA polymerase II promoter

Defense response

Cell communication

Response to stress* or wounding**

Chromosome segregation

Immune system process, Immune response

Kinetochore assembly

Signal transduction

Regulation of transcription DNA-dependent

Ion transport

Molecular function

Molecular function

(white shark)

(shared between teleosts and mammals)

Protein binding

DNA binding, or mismatch DNA binding

RNA polymerase II transcription mediator activity

Protein binding**, chemokine receptor binding**, interleukin binding**, interleukin-1 receptor binding*

DNA-directed RNA polymerase activity

Metal ion binding