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Table 2 Chromosomal regions (1 Mb resolution) with highest interaction frequencies (> = 30% in control condition; T0)

From: Genome-wide analysis uncovers high frequency, strong differential chromosomal interactions and their associated epigenetic patterns in E2-mediated gene regulation

Chromosome regions (interaction frequency > =30%)

T0 ChIP-seq maximum read count

T0 ChIP-seq binding sites

T0 interaction frequency%

T1 ChIP-seq maximum read count

T1 ChIP-seq binding sites

T1 interaction frequency%

chr3 62000001 63000000

6

0

31.4955

89

8

28.5573

chr3 63000001 64000000

16

5

32.1558

64

21

27.5008

chr3 64000001 65000000

8

8

44.5031

105

65

37.141

chr17 54000001 55000000

114

7

30.6042

308

46

25.7181

chr17 55000001 56000000

14

14

35.8864

95

62

31.9247

chr17 56000001 57000000

15

47

37.7022

110

132

32.4199

chr17 57000001 58000000

10

6

39.7161

169

36

34.2357

chr20 45000001 46000000

15

60

37.5041

244

148

31.4955

chr20 51000001 52000000

26

69

43.5787

325

182

36.4807

chr20 52000001 53000000

47

34

53.549

399

167

45.2955

  1. The corresponding interaction frequency in E2-treated condition (T1) is also listed. ChIP-seq read count represents ERα binding intensity, and ChIP-seq binding sites represent the number of binding sites.