Table 3 Recurrent mutations
From: Large-scale polymorphism discovery in macaque G-protein coupled receptors
| Â | Â | Â | Â | Â | Human | Macaque | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|
Gene | AA position | AA1 | AA2 | Consensus prediction | GRCh37.p5 | dbSNP | Human MAF | rheMac2 | Chinese MAF | Indian MAF | Fascicularis MAF |
FZD6 | 664 | A | E | Deleterious | chr8:104343607 | rs12549394 | 0.02 | chr8:105850125 | 0.00 | 0.00 | 0.10 |
GPR19 | 116 | V | I | Likely deleterious | chr12:12815037 | rs41276680 | 0.01 | chr11:13015710 | 0.02 | 0.00 | 0.22 |
GPR44 | 204 | V | A | Likely neutral | chr11:60620585 | rs2467642 | 0.01 | chr14:13261124 | 0.07 | 0.02 | 0.83 |
GPR78 | 342 | R | H | Deleterious | chr4:8589023 | rs9685931 | 0.11 | chr5:197204 | 0.05 | 0.00 | 0.00 |
GPR98 | 194 | P | H | Deleterious | chr5:89920969 | rs61745498 | 0.02 | chr6:86859930 | 0.00 | 0.05 | 0.00 |
GPR146 | 266 | V | M | Deleterious | chr7:1097947 | rs55677825 | 0.01 | chr3:38980764 | 0.14 | 0.00 | 0.00 |
GPR153 | 209 | R | H | Neutral | chr1:6313938 | rs12735670 | 0.31 | chr1:9260385 | 0.10 | 0.00 | 0.00 |
GPR156 | 798 | R | H | Likely neutral | chr3:119885931 | rs115365859 | 0.01 | chr2:40203636 | 0.00 | 0.00 | 0.14 |
MRGPRX3 | 198 | L | R | Likely deleterious | chr11:18159342 | rs28482781 | 0.02 | chr14:53770726 | 0.07 | 0.00 | 0.00 |