Table 4 Shared amino acid mutations
From: Large-scale polymorphism discovery in macaque G-protein coupled receptors
| Â | Â | Human | Macaque | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Gene | AA Position | AA1 | AA2 | Consensus Prediction | GRCh37.p5 | dbSNP | Human MAF | AA1 | AA2 | Consensus Prediction | rheMac2 | Chinese MAF | Indian MAF | Fascicularis MAF |
DRD5 | 330 | P | Q | Likely Neutral | chr4:9784642 | rs1800762 | 0.03 | P | L | Neutral | chr5:4664928 | 0.12 | 0.00 | 0.00 |
GPR78 | 318 | R | C | Likely Neutral | chr4:8588950 | rs61746144 | 0.01 | R | H | Neutral | chr5:197276 | 0.00 | 0.00 | 0.17 |
HTR1E | 208 | A | T | Likely Deleterious | chr6:87725674 | rs3828741 | 0.01 | A | S | Likely Neutral | chr4:82975291 | 0.00 | 0.03 | 0.00 |
MRGPRX1 | 55 | R | L | Deleterious | chr11:18956168 | rs55954376 | 0.01 | R | C | Deleterious | chr14:52926663 | 0.00 | 0.24 | 0.00 |
P2RY4 | 168 | V | M | Likely Neutral | chrX:69478973 | rs1152186 | 0.05 | V | A | Likely Neutral | chrX:69226991 | 0.07 | 0.00 | 0.00 |