The effect of proatherogenic pathogens on adipose tissue transcriptome and fatty acid distribution in apolipoprotein E-deficient mice

Table 2 A. actinomycetemcomitans infection-enriched GO terms in the inguinal AT transcriptome

GO category	Enriched GO term	GO term p-value^a	GO term-associated gene products
GO category	Enriched GO term	GO term p-value^a	Up-regulated^b	Down-regulated^b
GO:0005515	Protein binding	<0.001	Spon2, S100a8, Ltf, Des, Retnlg, D6Mit97, LOC100047788, Igl, Igh-V11, Ighg3, Igkv12-46, Igkv5-48, Igkv13-84, Igkv19-93, Igkv15-103	Zbtb7a, Rhob, Aldh1a1, Ywhag, Ccdc6, Ptplb, Antxr1, Timp4, Rps3a, Ddr2, Cidea, Nr1d2, G0s2, Lep, Acta1
GO:0019731	Antibacterial humoral response	0.009	LOC100047788	-
GO:0019730	Antimicrobial humoral response	0.009	LOC100047788	-
GO:0003823	Antigen binding	0.009	Igkv5-48, LOC100047788	-

^aP-values are corrected for multiple hypotheses using Benjamini-Hochberg false discovery rate.
^bFold change limit 2.0.
Number of biological replicates is 3.
GO, gene ontology. The maximum of 20 GO categories is shown.

ISSN: 1471-2164