Table 5 Differential expression of RNA transcripts as detected by a tiled oligonucleotide microarray

T1

3

303138-303295

157

Mb0258/nirB

A

3↑

nitrite reductase (large sub-unit)

T2

5

303260-303515

255

Mb0258/nirB

S

5↑

nitrite reductase (large sub-unit)

sSNP at 303227; C-T in 1307/01 only

T3

2

1105085-1105193

108

Mb1014

A

3↑

3↑

probable adhesion component of ABC transporter

T4

2

1105158-1105315

157

Mb1014

A

3↑

3↑

probable adhesion component of ABC transporter

T5

3

1105158-1105315

157

Mb1014

S

3↑

3↑

probable adhesion component of ABC transporter

T6

5

1778876-1779131

255

Mb1618c

A

9↑

possible secreted lipase

sSNP at 1778879; C-T in 1121/01 only

T7

2

1840174-1840282

108

Mb1672c

S

4↓

hypothetical protein

T8

3

1932158-1932315

157

tRNA-Pro

S

3↑

proline tRNA

T9

5

1932452-1932707

255

Mb1749c

S

4↑

toxin component of toxin-antitoxin system

nSNP at 1932704; C-T (G to D) in 1307/01 only

T10

5

1932746-1933075

329

Mb1750c

S

7↑

anti-toxin component of toxin-antitoxin system

T11

6

2122959-2123263

304

Mb1914c

A

12↑

probable short-chain type dehydrogenase/reductase

sSNP at 2122970; C-T in 2451/01 only

T12

2

2324463-2324571

108

Mb2110

S

3↑

hypothetical protein (frame-shifted in 2122/97)

T13

2

2328944-2329052

108

Mb2116c/pepE

S

2↓

3↓

probable dipeptidase

T14

2

2329483-2329591

108

Mb2117

A

10↓

10↓

5′-3′ exonuclease

nSNP at 2329583; A-G (comp. strand; I to T) in 2451/01 only

T15

3

2868310-2868467

157

Mb2607

A

6↓

8↓

hp (frame-shifted in 2122/97)

T16

2

2868506-2868614

108

Mb2607

A

7↓

7↓

hp (frame-shifted in 2122/97)

nSNP at 2868616; A-G (stop to W) in 2451/01 and 1307/01;

T17

2

3075740-3075848

108

I

5↑

6↑

T18

2

3075887-3075995

108

I

5↑

6↑

T19

2

3076622-3076730

108

I

4↑

4↑

T20

2

3076769-3076877

108

I

5↑

5↑

T21

2

3078728-3078836

108

I

6↑

7↑

T22

2

3079169-3079277

108

I

4↑

6↑

T23

2

3079903-3080011

108

I

6↑

7

T24

2

3844577-3844685

108

Mb3509c

S

3↑

3↑

possible acyltransferase (frame-shifted in 2122/97)

T25

6

4155501-4155805

304

Mb3803/echA21

A

5↑

possible enoyl-coA hydratase

sSNP at 4155803; C-T (comp. strand) in 2451/01 only

T26

2

4316987-4317095

108

Mb3927c

A

3↑

chp (frame-shifted in H37Rv)