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Figure 3 | BMC Genomics

Figure 3

From: Transcription-factor occupancy at HOT regions quantitatively predicts RNA polymerase recruitment in five human cell lines

Figure 3

Characterization of HOT regions with reference annotations. A: Overlap among promoter annotations. Each HOT region from the analysis of all canonical TFs in all cells (N = 7,227) was annotated with the nearest initiating RNA polymerase II peak, CAGE peak, or RefSeq TSS within 500 bp. B: Proximity of TFs’ binding regions to promoters, in base pairs, according to nondirectional RNA polymerase II ChIP-seq data, directional CAGE data, or RefSeq annotations of transcription start sites. C: Quantitative annotations versus presence of Pol II. Each row of figures shows distributions of a given annotation in the two combined and five cell-specific data sets, separated between HOT regions not at a consensus promoter (dark) vs. regions within 500 bp of a Pol II binding site, a CAGE peak, and a RefSeq TSS (light).

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BMC Genomics

ISSN: 1471-2164

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