Figure 6

Predictive value of all motifs for all TFs, in GM12878 cells. Each row represents a single TF, with replicates pooled. Each column represents one sequence motif from the previous analysis, and motif sets associated with the same TF are grouped. Color intensity represents the significance of the difference in occupancy of the given TF at consensus promoters with vs. without the given motif, where significance is the logarithm of the p-value from a t-test for the difference between means of occupancy scores, which are the means of variance-stabilized scores across replicates. Blue signifies enrichment of the given TF at sites with the given motif, and red signifies depletion of the given TF at sites with the given motif.