Figure 4

Odds ratios (ORs) of renal tumor incidence of (AIRmax x AIRmin)F2 mice by genotype at rs3719497 on chromosome 17, located near the peak LOD score of genetic linkage between renal tumor incidence and genomic variants. At the reference genotype GG, carried by AIRmax mice, renal tumors were observed in 4 of 163 F2 mice (2.5% incidence, reference category). At the GA genotype, renal tumors were seen in 110 of 361 mice (30.5%; OR = 14.4; 95% CI, 6.0 – 56.6), while at the AA genotype renal tumors were observed in 54 of 138 mice (39.1%; OR = 25.5; 95% CI, 8.5 – 86.1). ORs and 95% CIs are reported on a logarithmic scale.