Table 1 Probable participants of the DNA repair system in M. gallisepticum
DNA repair system | Gene name | Function | Presence in genome M. gallisepticum | Copy number of mRNA per one genome | Presence in proteome |
|---|---|---|---|---|---|
All systems | ligA | DNA ligase | + | 0.03 | + |
DNA methylation | hsdM | DNA-methyltransferase | + | nd | - |
MMR | Exo | 5′- 3′-exonuclease | + | nd | + |
MMR | hup2 | DNA-mismatch binding | + | 0.4 | + |
MMR | MGA_0793 | Putative vsr protein | + | nd | + |
MMR | MGA_0195 | Putative MutH analogue | + | nd | + |
NER and SOS | uvrA | Excinuclease ABC subunit A | + | 0.02 | + |
NER and SOS | uvrB | Excinuclease ABC subunit B | + | 0.02 | + |
NER and SOS | uvrC | Excinuclease ABC subunit C | + | 0.02 | + |
NER and MMR | uvrD | DNA helicase II | + | 0.04 | + |
BER | fpg (mutM) | Formamidopyrimidine-DNA glycosylase | + | 0.09 | + |
BER | Ung | Uracil-DNA glycosylase | + | 0.01 | - |
BER | Nfo | endonuclease IV | + | 0.08 | + |
Recombination and SOS | recA | Recombinase RecA | + | 0.01 | + |
Recombination and SOS | ruvA | Holliday junction ATP-dependent DNA helicase subunit A | + | 0.01 | - |
Recombination and SOS | ruvB | Holliday junction ATP-dependent DNA helicase subunit B | + | 0.01 | - |
Recombination | Smc | Chromosome cohesion | + | nd | + |
Recombination and SOS | recR | Recombination protein RecR | + | 0.02 | + |
Recombination | MGA_0016 | Recombination protein RecO | + | nd | - |
Recombination | recU | Holliday junction resolvase | + | nd | - |
Recombination | MGA_0836 | Holliday junction resolvase | + | nd | + |
SOS | dinB | DNA-polymerase IV | + | 0.01 | + |