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Table 2 ESC genes overexpressed in yHCC patients (q < 0.05, Young HCC vs. elder HCC)

From: Forfeited hepatogenesis program and increased embryonic stem cell traits in young hepatocellular carcinoma (HCC) comparing to elderly HCC

Probe set ID

UniGene ID

Gene title

Gene symbol

Location

Folds

219010_at

Hs.518997

chromosome 1 open reading frame 10

C1orf106

chr1q32.1

3.05

202715_at

Hs.377010

carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase

CAD

chr2p22-p21

1.68

1555772_a_at

Hs.437705

cell division cycle 25 homolog A (S. pombe)

*CDC25A

chr3p21

1.89

226980_at

Hs.482233

DEP domain containing 1B

DEPDC1B

chr5q12.1

2.08

201697_s_at

Hs.202672

DNA (cytosine-5-)-methyltransferase 1

*DNMT1

chr19p13.2

1.74

229115_at

Hs.649497

dynein, cytoplasmic 1, heavy chain 1

*DYNC1H1

chr14q32.3-qter

1.78

200005_at

Hs.55682

eukaryotic translation initiation factor 3, subunit D

EIF3D

chr22q13.1

1.55

1554576_a_at

Hs.434059

ets variant gene 4 (E1A enhancer binding protein, E1AF)

ETV4

chr17q21

2.02

220060_s_at

family with sequence similarity 222, member B

FAM222B

chr17q11.2

1.56

213008_at

Hs.513126

Fanconi anemia, complementation group I

*FANCI

chr15q26.1

1.78

219390_at

Hs.571333

FK506 binding protein 14, 22 kDa

FKBP14

chr7p15.1

1.72

223079_s_at

Hs.116448

glutaminase

GLS

chr2q32-q34

2.26

215942_s_at

Hs.386189

G-2 and S-phase expressed 1

*GTSE1

chr22q13.2-q13.3

1.94

242890_at

Hs.655830

Helicase, lymphoid-specific

*HELLS

chr10q24.2

2.47

212966_at

Hs.632767

hypermethylated in cancer 2

*HIC2

chr22q11.21

2.71

208930_s_at

Hs.465885

interleukin enhancer binding factor 3, 90 kDa

*ILF3

chr19p13.2

2.32

208974_x_at

Hs.532793

karyopherin (importin) beta 1

KPNB1

chr17q21.32

1.82

202726_at

Hs.1770

ligase I, DNA, ATP-dependent

*LIG1

chr19q13.2-q13.3

1.82

65588_at

Hs.400876

lncRNA LOC388796

LOC388796

65588_at

1.68

224473_x_at

Hs.523221

leucine zipper, putative tumor suppressor 2

*LZTS2

chr10q24

1.61

64432_at

Hs.333120

MAPKAPK5 antisense RNA 1

MAPKAPK5-AS1

chr12q24.12

1.61

242260_at

Hs.268939

Matrin 3

MATR3

chr5q31.2

2.35

235409_at

Hs.187569

MAX gene associated

MGA

chr15q14

1.79

228097_at

Hs.484738

myosin regulatory light chain interacting protein

MYLIP

chr6p23-p22.3

1.64

208752_x_at

Hs.524599

nucleosome assembly protein 1-like 1

NAP1L1

chr12q21.2

1.66

214107_x_at

Hs.740414

aminopeptidase puromycin sensitive

NPEPPS

chr17q21

1.85

200057_s_at

Hs.533282

non-POU domain containing, octamer-binding

*NONO

chrXq13.1

1.52

228566_at

Hs.464912

Cyclin-dependent kinase 2B-inhibitor-related protein

P15RS

chr18q12.2

1.51

203103_s_at

Hs.502705

PRP19/PSO4 pre-mRNA processing factor 19 homolog (S. cerevisiae)

*PRPF19

chr11q12.2

1.49

1555630_a_at

Hs.301853

RAB34, member RAS oncogene family

RAB34

chr17q11.2

3.14

206499_s_at

Hs.469723

regulator of chromosome condensation 1

*RCC1

chr1p36.1

1.59

200858_s_at

Hs.512675

ribosomal protein S8

RPS8

chr1p34.1-p32

1.36

209127_s_at

Hs.584842

squamous cell carcinoma antigen recognized by T cells 3

SART3

chr12q24.1

2.03

214728_x_at

Hs.327527

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, a4

*SMARCA4

chr19p13.2

1.61

201072_s_at

Hs.476179

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, c1

SMARCC1

chr3p23-p21

1.89

228990_at

Hs.632377

small nucleolar RNA host gene 12 (non-protein coding)

SNHG12

chr1p35.3

1.86

218324_s_at

Hs.654826

spermatogenesis associated, serine-rich 2

SPATS2

chr12q13.12

1.84

202826_at

Hs.233950

serine peptidase inhibitor, Kunitz type 1

SPINT1 (HAI-1)

chr15q15.1

3.36

200956_s_at

Hs.523680

structure specific recognition protein 1

*SSRP1

chr11q12

1.78

207627_s_at

Hs.48849

transcription factor CP2

TFCP2

chr12q13

1.66

212770_at

Hs.709205

transducin-like enhancer of split 3 (E(sp1) homolog, Drosophila)

TLE3

chr15q22

1.51

208837_at

Hs.513058

transmembrane emp24 protein transport domain containing 3

TMED3

chr15q24-q25

2.77

238797_at

Hs.13543

tripartite motif-containing 11

TRIM11

chr1q42.13

1.51

235476_at

Hs.212957

tripartite motif-containing 59

TRIM59

chr3q26.1

2.00

209053_s_at

Hs.113876

Wolf-Hirschhorn syndrome candidate 1

WHSC1

chr4p16.3

1.97

204799_at

Hs.475208

zinc finger, BED-type containing 4

ZBED4

chr22q13.33

1.72

228988_at

Hs.326801

zinc finger protein 711

ZNF711

chrXq21.1-q21.2

3.40

  1. *Genes discussed in the text.