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Table 5 Differential expression of genes related to the cell cycle & DNA replication

From: Inflammatory responses in primary muscle cell cultures in Atlantic salmon (Salmo salar)

Gene ID1

Annotation2

Mean fold change± SE3

Identity4

Ssa#S30294618

DW581582

2.4 ± 0.3

Cyclin D1

Ssa#S31971283

DY700073

2.4 ± 0.2

Cell division cycle associated 4 isoform 14

Ssa#S35549130

EG835508

2.2 ± 0.1

Cyclin G2

Ssa#S30291070

DW578034

−2.0 ± 0.1

Cyclin-dependent kinase 2 isoform 1

Ssa#STIR18340

TC78544

−2.1 ± 0.1

Cyclin B1

Omy#S19711047

CR367942

−2.1 ± 0.2

Cyclin B2

Ssa#S35661746

EG896464

−2.2 ± 0.2

Cell cycle progression 1 isoform 2

Ssa#S35547210

EG833588

−2.2 ± 0.1

Mediator of RNA polymerase II transcription subunit 22

Ssa#TC109012

TC109012

−2.6 ± 0.2

Cyclin E1 isoform 1

Ssa#KSS3754

NM_001173741

−2.8 ± 0.2

Minichromosome maintenance complex component 4

Ssa#STIR12008

TC69433

−3.0 ± 0.1

Cell division control protein 2

Ssa#TC103697_S

TC103697

−3.0 ± 0.1

DNA replication licensing factor mcm2

Ssa#S30290620

DW577584

−3.2 ± 0.1

Cyclin-dependent kinase 4

Ssa#S35659383

EG894101

−3.3 ± 0.1

Cyclin A2

Ssa#S18888540

CB514505

−4.2 ± 0.3

Minichromosome maintenance complex component 2

Ssa#S35699881

EG934599

−4.4 ± 0.1

Minichromosome maintenance complex component 3

Ssa#S35664683

EG899401

−4.8 ± 0.4

DNA replication complex GINS protein PSF1

Ssa#S30295467

DW582431

−5.1 ± 0.6

Spindle pole body component 24 homolog

Ssa#STIR15543

TC74419

−5.3 ± 0.5

Minichromosome maintenance complex component 7

Ssa#S18890448

CB516667

−6.7 ± 0.6

Minichromosome maintenance complex component 5

Ssa#S30277130

DW564098

−10.6 ± 0.4

Cell division cycle associated 7 isoform 1

Omy#S19711255

CR367985

−14.7 ± 8.7

Cyclin E2

Omy#S34311297

CU069027

−15.1 ± 2.8

Cell division cycle 6 protein

  1. List of selected mRNAs related to the cell cycle & DNA replication found to be increased or decreased in expression in response to rIL-1β stimulation. Genes were assigned to the table based upon both their GO identifier and previous knowledge of their functions. Genes with greatest fold differences in expression are presented, the genes that are lower in expression are denoted by (-) value. The genes shown were significant at p < 0.05 following t- tests with Benjamini-Hochberg FDR and greater than 2-fold change. 1Indicates the unique code for the feature on the microarray, 2Accession number of the cDNA sequence, accession numbers beginning with TC are for oligos from the TIGR Atlantic Salmon Gene Index. 3Fold change, in the case of oligos that featured multiple times in the gene list the one with the highest fold change is reported. 4Identity of the probe target as determined by BLASTX and BLASTN searches.