Figure 2

Global distribution of differentially regulated transcripts in virulent and attenuated T2Bo Babesia bovis strain pair and the breakdown of the putative functions of these transcripts. (A) Sixty-one genes were differentially expressed where 41% and 59% were upregulated in the virulent and attenuated strain, respectively. (B) Significantly upregulated genes in the virulent strain with corresponding putative functions. (C) Significantly upregulated genes in the attenuated derivative strain and their predicted functions. Ves, gene encoding for the variant erythrocyte surface antigen (VESA)1; sbp2, gene encoding for spherical body protein 2; smORF, gene encoding for small open reading frame protein; doxpr, gene encoding for 1-deoxy-D-xylose-5-phosphate reductoisomerase.