Table 3 Performance comparison of BS aligners on RRBS data
From: BS-Seeker2: a versatile aligning pipeline for bisulfite sequencing data
| Â | BS-Seeker2 | Bismark | BSMAP | |||
|---|---|---|---|---|---|---|
RRBS | Bowtie2 | Bowtie | Bowtie2 | Bowtie | (RRBSMAP) | |
| Â | local | e2e | (e2e) | |||
Simulation: error-free | ||||||
map | 78.29% | 78.02% | 78.29% | 72.51% | 78.08% | 78.63% |
acc | 100.00% | 100.00% | 100.00% | 100.00% | 100.00% | 99.82% |
Simulation: error-containing | ||||||
map | 79.18% | 78.42% | 78.72% | 71.36% | 78.17% | 79.10% |
acc | 98.11% | 98.59% | 99.02% | 99.61% | 98.82% | 98.81% |
Real data | ||||||
map | 64.45% | 48.78% | 47.29% | 44.24% | 46.89% | 45.64% |