Figure 6
From: Prioritizing genes responsible for host resistance to influenza using network approaches
Prioritized genes in apoptosis and TNFR2 signaling pathways. The graphical representation of the pathways is generated by the ingenuity pathway analysis (IPA) tool. The prioritized genes were highlighted by red dotted circles. The apoptosis and TNFR2 signaling pathways were extracted from the “canonical pathway” mappings. Genes are color coded by their differential expression levels between resistance and susceptible mouse strains. In particular, the genes with higher expression in susceptible mice than in resistance mice were colored red; whereas those having lower expression in susceptible than resistance mice were shown in green. The symbols used to represent molecules and relationships were illustrated in the legend.