Table 1 Ivy Center fusions
Ivy Center sample id | Fusion gene symbol (5′ → 3′) | Fusion junction reads | Genomic location (hg19) chromosome (strand) | Type |
|---|---|---|---|---|
(TCGA sample id) | Fusion transcripts (5′ → 3′) (UAR-genomic sequence without gene annotation) | WT junction reads (5′,3′) | Coordinates (5′,3′) |  |
SN214 | MON2 → MARS | 47 | 12q14 (+/+) | In-frame fusion |
(TCGA-74-6583) | (NM_015026 → NM_004990) | (6, 3) | (62981936, 57883990) |  |
SN214 | MDM1 → UAR | 196 | 12q15 (−/−) | Extended 3′ UTR |
(TCGA-74-6583) | (NM_020128 → NA) | (4, NA) | (68717849, 68876024) |  |
SN214 | SLC35E3 → UAR | 470 | 12q15 (+/−) | Truncated gene |
(TCGA-74-6583) | (NM_018656 → NA) | (0, NA) | (69145972, 68489752) |  |
SN238 | YEATS4 → SLC35E3 | 232 | 12q15 (+/+) | In-frame fusion |
|  | (NM_006530 → NM_018656) | (6, 4) | (69753803, 69152935) |  |
SN161 | PIK3C2B → DSTYK | 95 | 1q32 (−/−) | In-frame fusion |
|  | (NM_002646 → NM_199462) | (3, 0) | (204426856, 205119924) |  |
SN195-1 | PLEKHA6 → PIK3C2B | 23 | 1q32 (−/−) | 5′ UTR |
|  | (novel 5′ UTR → NM_002646) | (0, 13) | (204320007, 204439018) |  |
SN161 | CREB1 → PARD3B | 65 | 2q33 (+/+) | Out-of-frame fusion |
|  | (NM_004379 → NM_057177) | (10, 1) | (208442379, 205829875) |  |
SN214 | SCFD2 → CLOCK | 10 | 4q12 (−/−) | In-frame fusion |
(TCGA-74-6583) | (NM_152540 → NM_004898) | (4, 6) | (53786892, 56301763) |  |
SN159 | SEC61G → UAR | 484 | 7p11 (+/−) | No protein product |
|  | (ENST00000480303 → NA) | (44, NA) | (51654097, 54821716) |  |
SN161 | LANCL2 → RP11-745C15 | 274 | 7p11 (+/+) | Truncated gene |
|  | (NM_018697 → ENST00000439413) | (8, 0) | (55469013, 54872359) |  |
SN218 | ZNF713 → UAR | 51 | 7p11 (+/+) | Truncated gene |
|  | (uc003tra → NA) | (2, NA) | (55991300, 56082944) |  |
SN154 | ZNF713 → UAR | 14 | 7p11 (+/−) | Truncated gene |
(TCGA-74-6573) | (uc003tra → NA) | (10, NA) | (55980418, 55945274) |  |
SN187 | FGFR3 → TACC3 | 13 | 4p16 (+/+) | In-frame fusion |
(TCGA-74-6578) | (NM_000142 → NM_006342) | (31, 0) | (1808661, 1737458) |  |