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Table 1 Top 20 potential SUMO-1 targeting TFs before KSHV reactivation

From: The chromatin modification by SUMO-2/3 but not SUMO-1 prevents the epigenetic activation of key immune-related genes during Kaposi’s sarcoma associated herpesvirus reactivation

Rank Name Transfac TFBS # (in TSS±500 bp) Peak # of TFBS (in TSS±500 bp) % of TFBS Peak (in TSS±500 bp) Gene #
0 h 12 h 0 h 12 h 0 h 12 h
1 ETS1 V$CETS1P54_01 1587 341 262 21.5% 16.5% 294 229
2 GABPA/NRF-2 V$NRF2_01 1577 336 237 21.3% 15.0% 286 206
3 ELK1 V$ELK1_02 1667 333 254 20.0% 15.2% 279 215
4 USF1 V$USF_C 441 79 45 17.9% 10.2% 71 44
V$USF_Q6 1136 146 97 12.9% 8.5% 132 92
5 STAT1 V$STAT1_03 282 50 41 17.7% 14.5% 48 39
V$STAT1_01 1179 146 122 12.4% 10.3% 134 110
6 STAT4 V$STAT4_01 106 17 17 16.0% 16.0% 4 4
7 MYC/MAX V$MYCMAX_02 580 90 76 15.5% 13.1% 68 55
V$MYCMAX_01 784 104 88 13.3% 11.2% 93 68
8 CREB1 V$CREB_01 666 103 87 15.5% 13.1% 97 83
9 MAX V$MAX_01 584 87 68 14.9% 11.6% 75 64
10 ATF-2 V$CREBP1_01 272 37 30 13.6% 11.0% 35 28
11 STAT3 V$STAT3_01 986 133 108 13.5% 11.0% 123 101
12 SREBF1/SREBP1 V$SREBP1_01 1038 140 108 13.5% 10.4% 110 93
13 MYCN V$NMYC_01 1467 195 125 13.3% 8.5% 170 114
14 STAT6 V$STAT_01 570 75 59 13.2% 10.4% 66 54
15 ARNT V$ARNT_01 835 108 89 12.9% 10.7% 102 87
16 ARID5B/MRF2 V$MRF2_01 478 61 57 12.8% 11.9% 56 52
17 E2F1/2/3/4/5 V$E2F_02 1301 166 121 12.8% 9.3% 149 110
18 PBX1 V$PBX1_01 220 28 21 12.7% 9.5% 28 21
  1. bold: transcription factor with evidence of SUMO modification.