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Table 4 Top 20 potential SUMO-2/3 targeting TFs after KSHV reactivation

From: The chromatin modification by SUMO-2/3 but not SUMO-1 prevents the epigenetic activation of key immune-related genes during Kaposi’s sarcoma associated herpesvirus reactivation

Rank Name Transfac TFBS # (in TSS±500 bp) Peak # of TFBS (in TSS±500 bp) % of TFBS Peak (in TSS±500 bp) Gene #
0 h 12 h 0 h 12 h 0 h 12 h
1 STAT1 V$STAT1_03 282 53 79 18.8% 28.0% 45 68
2 ETS1 V$CETS1P54_01 1587 337 397 21.2% 25.0% 296 353
3 PBX1 V$PBX1_01 220 28 55 12.7% 25.0% 28 54
4 ATF2 V$CREBP1_01 272 45 67 16.5% 24.6% 45 64
5 CREB1 V$CREB_01 666 124 164 18.6% 24.6% 114 152
6 GABPA/NRF-2 V$NRF2_01 1577 320 379 20.3% 24.0% 274 335
7 ELK1 V$ELK1_02 1667 336 382 20.2% 22.9% 285 328
8 IRF-1 V$IRF1_01 534 46 118 8.6% 22.1% 43 113
9 STAT6 V$STAT_01 570 92 122 16.1% 21.4% 85 110
10 FOXO4 V$FOXO4_02 456 28 97 6.1% 21.3% 28 75
11 NFATC1/2/3/4 V$NFAT_Q6 487 50 102 10.3% 20.9% 29 55
12 ARID5B/MRF2 V$MRF2_01 478 74 100 15.5% 20.9% 68 91
13 IRF-2 V$IRF2_01 601 48 125 8.0% 20.8% 63 93
14 SRY V$SRY_01 523 32 108 6.1% 20.7% 30 91
15 HLF V$HLF_01 438 69 90 15.8% 20.5% 66 85
16 IRF-7 V$IRF7_01 754 87 153 11.5% 20.3% 79 126
17 MEF2A V$MEF2_01 455 36 91 7.9% 20.0% 28 72
18 GATA1 V$GATA1_04 191 14 38 7.3% 19.9% 13 35
19 POU3F2 V$POU3F2_02 246 17 48 6.9% 19.5% 17 43
20 USF1 V$USF_C 441 69 86 15.6% 19.5% 64 78
  1. bold: transcription factor with evidence of SUMO modification.