|
Pathogen-influenced signaling
|
Virus entry via endocytic pathways
|
99
|
31
|
1.41E-03
|
28
|
3.24E-03
|
20
|
5.13E-03
|
|
Cellular immune response
|
Antigen Presentation pathway
|
40
|
14
|
1.26E-02
|
12
|
3.63E-02
|
9
|
3.24E-02
|
| |
CD40 signaling
|
70
|
23
|
2.82E-03
|
21
|
4.79E-03
|
14
|
1.91E-02
|
| |
HMGB1 signaling
|
99
|
25
|
9.33E-02
|
24
|
6.46E-02
|
16
|
1.03E-01
|
| |
IL-10 signaling
|
78
|
19
|
9.55E-02
|
16
|
2.07E-01
|
11
|
2.10E-01
|
| |
IL-15 signaling
|
67
|
20
|
1.86E-02
|
19
|
1.55E-02
|
16
|
2.34E-03
|
| |
IL-3 signaling
|
74
|
23
|
1.41E-02
|
22
|
1.02E-02
|
14
|
4.90E-02
|
| |
IL-8 signaling
|
205
|
48
|
4.68E-02
|
44
|
6.92E-02
|
27
|
2.14E-01
|
| |
NF-κB activation by viruses
|
82
|
23
|
2.00E-02
|
21
|
3.16E-02
|
15
|
3.39E-02
|
| |
p38 MAPK signaling
|
117
|
26
|
3.80E-01
|
24
|
3.88E-01
|
16
|
3.79E-01
|
| |
Toll-like receptor signaling
|
62
|
17
|
5.75E-02
|
15
|
9.55E-02
|
11
|
7.76E-02
|
|
Cytokine signaling
|
IL-17A signaling in airway cells
|
72
|
21
|
1.35E-02
|
2
|
8.51E-02
|
11
|
1.58E-01
|
| |
Prolactin signaling
|
80
|
22
|
3.72E-02
|
22
|
1.45E-02
|
17
|
6.46E-03
|
|
Cancer
|
Glioma signaling
|
112
|
29
|
1.55E-02
|
27
|
1.62E-02
|
19
|
2.14E-02
|
| |
p53 signaling
|
96
|
32
|
1.48E-03
|
27
|
1.23E-02
|
20
|
8.51E-03
|
| |
Small cell lung cancer signaling
|
89
|
27
|
6.03E-04
|
26
|
3.63E-04
|
20
|
2.57E-04
|
|
Cellular growth, proliferation and development
|
Cleavage and polyadenylation of pre-mRNA
|
12
|
5
|
8.32E-02
|
5
|
6.03E-02
|
4
|
5.01E-02
|
| |
EGF signaling
|
62
|
21
|
2.88E-03
|
20
|
2.34E-03
|
13
|
1.66E-02
|
| |
FAK signaling
|
101
|
27
|
1.32E-02
|
26
|
9.33E-03
|
17
|
3.47E-02
|
| |
JAK/Stat signaling
|
70
|
26
|
5.37E-04
|
24
|
8.71E-04
|
20
|
1.07E-04
|
| |
Oncostatin M signaling
|
35
|
12
|
3.55E-02
|
11
|
4.47E-02
|
8
|
5.01E-02
|
| |
PDGF signaling
|
85
|
25
|
1.07E-02
|
24
|
6.92E-03
|
18
|
5.01E-03
|
| |
Thrombopoietin signaling
|
63
|
17
|
4.90E-02
|
17
|
2.29E-02
|
12
|
3.31E-02
|
| |
VEGF signaling
|
103
|
25
|
7.59E-02
|
25
|
3.47E-02
|
16
|
9.55E-02
|
|
Cell cycle regulation
|
Cyclins and cell cycle regulation
|
89
|
24
|
2.75E-02
|
23
|
2.19E-02
|
13
|
1.80E-01
|
| |
GADD45 signaling
|
22
|
9
|
8.51E-03
|
8
|
2.40E-02
|
4
|
2.26E-01
|
| |
Mitotic roles of polo-like kinase
|
70
|
18
|
1.39E-01
|
18
|
7.24E-02
|
9
|
4.44E-01
|
|
Growth Ffactor signaling
|
ErbB2-ErbB3 signaling
|
60
|
19
|
1.82E-02
|
19
|
7.08E-03
|
15
|
3.02E-03
|
|
Apoptosis
|
April mediated signaling
|
43
|
13
|
3.72E-02
|
11
|
9.12E-02
|
6
|
3.24E-01
|
| |
Aryl hydrocarbon receptor signaling
|
161
|
40
|
1.48E-02
|
34
|
6.92E-02
|
21
|
1.96E-01
|
| |
Myc mediated apoptosis signaling
|
60
|
20
|
1.05E-02
|
19
|
8.71E-03
|
14
|
9.33E-03
|
|
Cellular stress and injury
|
Endoplasmic reticulum stress pathway
|
18
|
7
|
6.03E-02
|
7
|
3.98E-02
|
4
|
1.73E-01
|
|
Disease-specific pathways
|
Parkinson’s signaling
|
16
|
4
|
4.32E-01
|
4
|
3.61E-01
|
-
|
-
|
|
Neurotransmitters and other nervous system signaling
|
Cholecystokinin/gastrin-mediated signaling
|
106
|
24
|
2.59E-01
|
20
|
4.56E-01
|
-
|
-
|
