Skip to main content

Advertisement

Table 1 List of most significantly up-regulated genes in in vitro activated T cells of psoriasis patients compared to healthy controls

From: Genome-wide transcriptional analysis of T cell activation reveals differential gene expression associated with psoriasis

Probe Gene Fold change P value* Full name
Upregulated genes
ILMN_1683678 SPATS2L 1.37 0.0009 Spermatogenesis associated, serine-rich 2-like
ILMN_1735014 KLF6 1.32 0.0012 Kruppel-like factor 6
ILMN_1703263 SP140 1.38 0.0025 SP140 nuclear body protein
ILMN_2322498 RORA 1.31 0.0041 RAR-related orphan receptor A
ILMN_2246956 BCL2 1.23 0.0062 B-cell CLL/lymphoma 2
ILMN_2397721 GLB1 1.23 0.0062 Galactosidase, beta 1
ILMN_1781285 DUSP1 1.21 0.0071 Dual specificity phosphatase 1
ILMN_2321064 BAX 1.24 0.0096 BCL2-associated X protein
ILMN_1731107 CCDC92 1.33 0.0136 Coiled-coil domain containing 92
ILMN_1729749 HERC5 1.72 0.0267 Hect domain and RLD 5
ILMN_2095660 TMEM156 1.29 0.0453 Transmembrane protein 156
ILMN_1681301 AIM2 1.42 0.0464 Absent in melanoma 2
ILMN_1767470 SCPEP1 1.26 0.0469 Serine carboxypeptidase 1
Downregulated genes
ILMN_1778617 TAF9 −1.25 0.0009 TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDa
ILMN_2143250 FAR1 −1.20 0.0207 Fatty acyl CoA reductase 1
ILMN_1720114 GMNN −1.20 0.0269 Geminin
ILMN_2135175 SNORD36A −1.27 0.0303 Small nucleolar RNA, C/D box 36A
  1. *Multiple-test corrected p-value.
  2. List of genes with multiple-test corrected p-value < 0.05 and absolute change >1.2. Genes are classified into up-regulated or down-regulated groups and sorted by their statistical significance. Genes that were selected to validate are highlighted in bold.